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Erik Bruyneel Selected Research

alpha Catenin (alpha E-Catenin)

2/2008Insulin-like growth factor-I receptor, E-cadherin and alpha v integrin form a dynamic complex under the control of alpha-catenin.
2/2004Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells.
3/2002Structure and function of the N-cadherin/catenin complex in retinoblastoma.

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Erik Bruyneel Research Topics

Disease

29Neoplasms (Cancer)
05/2009 - 01/2002
14Colonic Neoplasms (Colon Cancer)
02/2008 - 04/2002
7Colorectal Neoplasms (Colorectal Cancer)
08/2007 - 09/2002
6Neoplasm Metastasis (Metastasis)
12/2007 - 04/2002
5Breast Neoplasms (Breast Cancer)
10/2006 - 01/2005
4Carcinogenesis
05/2009 - 05/2004
4Carcinoma (Carcinomatosis)
08/2007 - 05/2003
2Adenoma (Adenomas)
08/2007 - 04/2006
2Inflammation (Inflammations)
07/2003 - 04/2002
1Aberrant Crypt Foci
08/2007
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
08/2007
1Colitis
08/2007
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
04/2006
1Blood Coagulation Disorders
12/2005
1Hypoxia (Hypoxemia)
12/2005
1Venous Thrombosis (Deep-Vein Thrombosis)
12/2005
1Kidney Neoplasms (Kidney Cancer)
12/2005

Drug/Important Bio-Agent (IBA)

11Cadherins (E-Cadherin)IBA
03/2009 - 01/2002
9Collagen Type I (Type I Collagen)IBA
05/2009 - 01/2002
7Proteins (Proteins, Gene)FDA Link
05/2009 - 09/2003
5matrigelIBA
05/2009 - 06/2004
5beta CateninIBA
03/2009 - 03/2002
4Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA
09/2006 - 06/2002
4Trefoil FactorsIBA
01/2005 - 01/2003
4Peptides (Polypeptides)IBA
01/2005 - 07/2003
4CateninsIBA
02/2004 - 03/2002
3Cell Adhesion MoleculesIBA
02/2008 - 07/2003
3alpha Catenin (alpha E-Catenin)IBA
02/2008 - 03/2002
3IntegrinsIBA
12/2007 - 01/2004
3Pharmaceutical PreparationsIBA
05/2007 - 08/2006
3Neurotensin Receptors (Neurotensin Receptor)IBA
09/2006 - 04/2006
3Matrix Metalloproteinases (MMPs)IBA
06/2006 - 07/2003
3Transforming Growth Factor beta (TGF-beta)IBA
09/2004 - 01/2004
2Protein Isoforms (Isoforms)IBA
05/2009 - 01/2005
2Phosphotransferases (Kinase)IBA
12/2007 - 09/2002
2src-Family KinasesIBA
12/2007 - 08/2006
2Carrier Proteins (Binding Protein)IBA
12/2007 - 09/2006
2LipidsIBA
12/2007 - 01/2005
2GelsolinIBA
09/2007 - 12/2002
2Cisplatin (Platino)FDA LinkGeneric
09/2006 - 08/2006
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
08/2006 - 01/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2006 - 01/2005
2ThrombinFDA Link
12/2005 - 04/2002
2Proteinase-Activated ReceptorsIBA
12/2005 - 04/2002
2GelsIBA
12/2005 - 02/2004
2Trefoil Factor-3IBA
01/2005 - 01/2003
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
05/2004 - 05/2004
2ThromboxanesIBA
05/2004 - 05/2004
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2004 - 05/2004
2serpentine (alkaloid)IBA
05/2004 - 05/2004
2Malondialdehyde (Propanedial)IBA
05/2004 - 05/2004
2MutagensIBA
05/2004 - 05/2004
2ProstaglandinsIBA
05/2004 - 05/2004
2Arachidonic Acid (Vitamin F)IBA
05/2004 - 05/2004
2Metalloproteases (Metalloproteinases)IBA
09/2003 - 01/2002
2spasmolytic polypeptideIBA
07/2003 - 01/2003
1Small Interfering RNA (siRNA)IBA
05/2009
1Integrin alphaVIBA
02/2008
1PaxillinIBA
12/2007
1TetraspaninsIBA
12/2007
1TalinIBA
12/2007
1Ether (Diethyl Ether)IBA
12/2007
1Focal Adhesion Protein-Tyrosine KinasesIBA
12/2007
1Conditioned Culture MediaIBA
08/2007
1CytokinesIBA
08/2007
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
08/2007
1Bone Morphogenetic Protein 7IBA
08/2007
1Tumor Biomarkers (Tumor Markers)IBA
05/2007
1SynteninsIBA
05/2007
1Delta CateninIBA
10/2006
1GuanineIBA
09/2006
1CalciumIBA
09/2006
1Farnesyltranstransferase (Farnesyltransferase)IBA
09/2006
1Cyclic AMP (AMP, Cyclic)IBA
09/2006
1Topoisomerase InhibitorsIBA
09/2006
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
09/2006
1BIM 46174IBA
09/2006
1Frizzled ReceptorsIBA
09/2006
1Hormones (Hormone)IBA
09/2006
1DNA (Deoxyribonucleic Acid)IBA
08/2006
1plexinIBA
08/2006
1ZD 4190IBA
08/2006
1human VEGFA proteinIBA
08/2006
1N- (2- chloro- 5- methoxyphenyl)- 6- methoxy- 7- ((1- methyl- 4- piperidinyl) methoxy) 4-quinazolinamineIBA
08/2006
1NeuropilinsIBA
08/2006
1Semaphorins (Semaphorin)IBA
08/2006
1Semaphorin-3AIBA
08/2006
1NeurotensinIBA
06/2006
1SR 48692IBA
06/2006
1RNA (Ribonucleic Acid)IBA
06/2006
1GelatinasesIBA
06/2006
1TCF Transcription FactorsIBA
04/2006
1Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
12/2005
1rho-Associated KinasesIBA
12/2005
1FibrinIBA
12/2005
1Cysteine (L-Cysteine)FDA Link
12/2005
1Transcription Factors (Transcription Factor)IBA
07/2005
1Estrogens (Estrogen)FDA Link
05/2005

Therapy/Procedure

1Activator Appliances (Function Activator)
05/2009
1Oral Administration
08/2006